BPC-157

$59.50

BPC-157 is a synthetic pentadecapeptide (15 amino acids) originally identified as a fragment sequence associated with larger gastric-derived “body protection compound” research. In laboratory settings, BPC-157 is studied as a research peptide for exploring cellular signaling involved in tissue response to injury, including pathways related to fibroblast activity, extracellular matrix (ECM) organization, and endothelial cell behavior.

Preclinical and in vitro studies commonly evaluate BPC-157 in models that measure cell migration, cell survival, angiogenesis-related signaling, and oxidative stress biomarkers under controlled conditions. Because these endpoints are quantifiable in cell culture systems and animal models, BPC-157 is frequently used to probe mechanisms of tissue repair biology, vascular recruitment/collateralization, and inflammation-linked signaling cascades, without implying human outcomes.

For research use only. Not for human consumption.

References:
Sikiric P et al., Curr Pharm Des, 2018;24(18):2002–2030
Kang EA et al., Dig Dis Sci, 2013;58:3310–3317
Seiwerth S et al., Biomedicines, 2018;6(3):75

Category:
Description
Properties
Molecular Formula C62H98N16O22
Molecular Weight 1419.5
Monoisotopic Mass 1418.70415882
Polar Area 573
Complexity 3040
XLogP -9
Heavy Atom Count 100
Hydrogen Bond Donor Count 16
Hydrogen Bond Acceptor Count 24
Rotatable Bond Count 39
PubChem LCSS Bpc-157 Laboratory Chemical Safety Summary
Identifiers
CID 9941957
InChI InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43,50H,7-30,63-64H2,1-6H3,(H,65,88)(H,66,93)(H,67,90)(H,68,94)(H,69,79)(H,70,80)(H,71,81)(H,72,89)(H,73,91)(H,74,92)(H,82,83)(H,84,85)(H,86,87)(H,99,100)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-/m0/s1
InChIKey HEEWEZGQMLZMFE-RKGINYAYSA-N
Isometric SMILES C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN
Canonical SMILES CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C2CCCN2C(=O)C3CCCN3C(=O)C4CCCN4C(=O)C(CCC(=O)O)NC(=O)CN
IUPAC Name (4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid
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