Acetyl Hexapeptide-3 (Argireline) 200mg (Topical)

$90.00

Acetyl Hexapeptide-3 (Argireline) is a synthetic hexapeptide studied in laboratory settings for its interaction with proteins involved in neurotransmitter release. Acetyl Hexapeptide-3 (Argireline) peptide research primarily examines its role in modulating components of the SNARE complex that regulate vesicle docking and acetylcholine release at the cellular level. As a short-chain peptide analog, it is investigated in biochemical and cell-based models to understand how peptide-mediated interference may influence neurotransmission-related pathways.

In vitro studies typically evaluate changes in neurotransmitter release, vesicle fusion dynamics, and expression of synaptic regulatory proteins under controlled experimental conditions. Additional research areas include peptide stability, skin-model penetration behavior, and interaction with other signaling-modulating peptides in reconstructed tissue systems. These biological systems are relevant in laboratory research because they provide measurable endpoints for examining synaptic protein interactions and peptide-driven modulation of cellular communication without implying human or cosmetic application.

For research use only. Not for human consumption.

References:
Blanes-Mira C et al., Int J Cosmet Sci, 2002 24(5):303–310
Daines AM et al., Peptides, 2010 31(10):1994–2001
Calvo P et al., J Cosmet Dermatol, 2015 14(1):27–35

Category:
Description
Properties
Molecular Formula C34H60N14O12S
Molecular Weight 889
Monoisotopic Mass 888.42358458
Polar Area 489
Complexity 1610
XLogP -6.3
Heavy Atom Count 61
Hydrogen Bond Donor Count 14
Hydrogen Bond Acceptor Count 15
Rotatable Bond Count 32
PubChem LCSS Argireline acetate Laboratory Chemical Safety Summary
Identifiers
CID 11228338
InChI InChI=1S/C34H60N14O12S/c1-17(49)43-20(8-11-25(51)52)29(57)47-22(9-12-26(53)54)31(59)48-23(13-16-61-2)32(60)46-21(7-10-24(35)50)30(58)45-19(6-4-15-42-34(39)40)28(56)44-18(27(36)55)5-3-14-41-33(37)38/h18-23H,3-16H2,1-2H3,(H2,35,50)(H2,36,55)(H,43,49)(H,44,56)(H,45,58)(H,46,60)(H,47,57)(H,48,59)(H,51,52)(H,53,54)(H4,37,38,41)(H4,39,40,42)/t18-,19-,20-,21-,22-,23-/m0/s1
InChIKey RJZNPROJTJSYLC-LLINQDLYSA-N
Isometric SMILES CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N
Canonical SMILES CC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCSC)C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N
IUPAC Name (4S)-4-acetamido-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
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